The Need of
Wonderdrink 6
Heart disease is the cause of the highest mortality rate in Malaysia. From 2015, until 2020, the latest statistics show that cardiovascular disease has always been the top cause of death for 14 years continuously. . According to the latest statistics, the rate of death from cardiovascular disease is as high as 69.4% for men and 30.6% for women.
Malaysia has the highest adult obesity rate in Southeast Asia. In the 2019 National Health and Morbidity Survey, it was reported that 50.1% of our adult population are overweight (30.4%) or obese (19.7%). Obesity is a risk factor for non-communicable diseases (NCD), such as type 2 diabetes, cardiovascular disease, and various cancers such as breast, colorectal, pancreatic, and kidney cancer. Compared with people of normal weight, obesity increases the risk of type 2 diabetes by 7 times in men and 12 times in women.
THE SYMPTOM OF HEART ATTACK
- Numbness / pain of limbs
- Tired and weak frequently
- Palpitation, chest tightness)
- Short of breath
- Headache / dizziness
High risk group
- Obese people
- People with chronic disease
- Men who over age of 40
- Night owl (who stay awake in the night)
- People with poor eating habits / people who eat less vegetables
- Smoking and drinking
- People who attend gathering, or event often
Looking alike?
Blood vessel blockage just like a congested traffic, fat that deposit in your blood vessels act like a Police Checking. This buildup fatty material can suddenly burst, followed by a blood clot(thrombus). When arterial thrombosis occurs in coronary arteries, can lead to a heart attack. When arterial thrombosis occurs in a blood vessel in the brain, can lead to a stroke.
Research & Development
Traditional Formulation, Scientifically Proven!
Hyperlipidemia is abnormal of lipid metabolism that presents in the bloodstream. The study aims is to investigate the effects of ZACA extract in rats fed high cholesterol diet (HCD) in vitro and vivo.
MSU hyperlipidaemia research timeline
2019.04
Stage 1 | Connected with the professional
This work was supported by Management & Science University (MSU) under Grant [MSU-RMC-02/FR01/08/L3/***] and the company providing ZACA extracts (wonderdrink6).
In this research, wonderdrink6 is called ZACA extracts. It’s an abbreviation form of Zinger officinale(Ginger), Allium sativum(Garlic), Citrus(Lemon), honey, and Malus domestica (Apple Cider)vinegar.
2019.05
Stage 3 | Research starts
ZACA extract has provided by Wonderdrink for hyperlipidaemia research.
Meeting up with Professor Dr. Norshararina Shari & Santhra Segaran Balan.
2019.05
Stage 3 | Study's on going
6 groups of rats were put into research and observed by twice a day basis. Person in charge cleans the containers on daily basis, clearing off the leftover and faeces.
N.C. - Normal chow Diet (this is a reference group)
P.C. - High Cholesterol Diet
D.C. - High Cholesterol Diet, Simvastatin Drug control
W1 - High Cholesterol Diet, Consuming wonderdrink6 1mg per kg, Or equivalent to 6ml For human
W2 - High Cholesterol Diet, Consuming wonderdrink6 3mg per kg, Or equivalent to 18ml For human
W3 - High Cholesterol Diet, Consuming wonderdrink6 5mg per kg, Or equivalent to 30ml For human
2019.06
Stage 3 | Research on going
During an informal discussion between MSU and Natural Tone, we found out there is nothing changed in rats from the vivo: the only difference is group NC (normal chow diet) rats are slimmer.
2019.07
Stage 3 | Research on going
9 weeks has past. Researchers realized rat groups that administered with ZACA extracts are generally bigger than the others. Sample tested on scale shows the same too: the mentioned groups were heavier. This might be due to extra calories consumed. Both MSU and Natural Tone were worried the result will come out unexpectedly.
2019.11
Stage 4 | Sample collection
18 weeks over. Proceed to sample collection step.
At the end of the study, the rats were fasting for 12 hours. Thereafter, the rats were anesthetized with diethyl ester. The blood samples were obtained by using the cardiac puncture method. Then, the blood samples were centrifuged (3000 rpm for 15 minutes) to separate the serum. The serum (supernatant) was removed and stored at -20°C for biochemical assay. Liver, kidney, retroperitoneal adipose tissue (RpWAT), visceral fat, gonadal fat were removed, washed with saline, and weighed. The parts of the liver, kidney, RpWAT tissue were fixed in 10% NBF (neutral buffered formalin) for histological examination.
2020.09.06
First Draft has completed.
First Draft has completed.
Written by Kokila Vani Perumal.
2020.10
Result is realised
Result and discussion
Based on vitro data, ZACA extracts had ORAC value 2000 μmol TE/100 mL, TPC (7537 ± 54.5%), 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity (27.34 ± 2.71%) , Elastase inhibitory assay (29.29 ± 1.65%) and Lipoxygenase inhibitory assay (98.58 ± 1.42%). Based on vivo data, ZACA extracts treated groups reduced in bodyweight, organ weights (Liver, Adipose tissue, Kidney) and positive improvement in blood toxicity (Creatinine, AST, ALT) and lipid profile (TC, TG, LDL, HDL).
In conclusion: The results demonstrate that ZACA extracts have a hyperlipidemic activity that can be an alternative approach to combat hyperlipidemia complications
2020.11.20
Participate international scientific competition.
Management and Science University (MSU) participate in virtual 31st International Invention, Innovation & Technology Exhibition (ITEX’20), Malaysia. This Hyperlipidaemia research has won GOLD medal in Health, beauty and sports category.
2021.04.02
Participate international scientific competition.
Management and Science University (MSU) participate in virtual Malaysia Technology Expo (MTE2021), Malaysia. This Hyperlipidaemia research has won GOLD Medal in healthcare, personal care, biotechnology and life sciences category.
Certifications
Wonderdrink 6 Concentrate Botanical Beverage does not contain any artificial flavor, coloring, saccharin, hormone, preservative, or any other chemical additives.
Product certifications issued by including SGS (the world’s leading inspection company). The company has Halal certification, Mesti certification, FoSIM registration at ministry of health of Malaysia.
"One of the biggest challenge for Malaysia is not only the economy itself but the increasing government medical spending for its citizens. and among of those diseases, ischaemic heart disease is the worst."
Shaiful Shah Rani
Wonderdrink6 Co Founder
Testimonials
Wonderdrink 6
Serving suggestion
1 bottle per serving, twice a day in the morning and evening. Shake well before drink.Take 2 bottles if have vessel blockage issue. Consume after meal if have gastric problem.
