Keperluan
Wonderdrink 6
Penyakit jantung adalah penyebab kadar kematian tertinggi di Malaysia. Dari 2015, sehingga 2020, statistik terkini menunjukkan bahawa penyakit kardiovaskular sentiasa menjadi punca utama kematian selama 14 tahun secara berterusan. . Menurut statistik terkini, kadar kematian akibat penyakit kardiovaskular adalah setinggi 69.4% bagi lelaki dan 30.6% bagi wanita.
Malaysia mempunyai kadar obesiti dewasa tertinggi di Asia Tenggara. Dalam Tinjauan Kesihatan dan Morbiditi Kebangsaan 2019,telah dilaporkan bahawa 50.1% daripada populasi dewasa kita berlebihan berat badan (30.4%) atau obes (19.7%). Obesiti adalah faktor risiko penyakit tidak berjangkit (NCD), seperti diabetes jenis 2, penyakit kardiovaskular, dan pelbagai kanser seperti kanser payudara, kolorektal, pankreas dan buah pinggang. Berbanding dengan orang yang mempunyai berat badan normal, obesiti meningkatkan risiko diabetes jenis 2 sebanyak 7 kali pada lelaki dan 12 kali pada wanita.
SIMPTOM SAKIT JANTUNG
- Kebas /sakit anggota badan
- Letih dan kerap lemah
- Palpitasi, sesak dada
- Sesak nafas
- Sakit kepala / pening
KUMPULAN BERISIKO TINGGI
- Orang gemuk
- Orang yang mempunyai penyakit kronik
- Lelaki yang berumur lebih dari 40 tahun
- Burung hantu malam (yang berjaga pada waktu malam)
- Orang yang kurang tabiat makan / orang yang kurang makan sayur
- Merokok dan minum
- Orang yang sering menghadiri perhimpunan, atau acara
Nampak serupa?
Salur darah tersumbat sama seperti lalu lintas yang sesak, lemak yang memendap dalam saluran darah anda bertindak seperti Pemeriksaan Polis. Bahan lemak terkumpul ini boleh pecah secara tiba-tiba, diikuti dengan bekuan darah (trombus). Apabila trombosis arteri berlaku dalam arteri koronari, ia boleh menyebabkan serangan jantung. Apabila trombosis arteri berlaku dalam saluran darah di otak, boleh menyebabkan strok.
Penyelidikan & Pembangunan
Fomulasi traditional, Terbukti secara saintifik!
Hiperlipidemia adalah abnormal metabolisme lipid yang terdapat dalam aliran darah. Kajian ini bertujuan untuk menyiasat kesan ekstrak ZACA dalam tikus yang diberi diet kolesterol tinggi (HCD) secara in vitro dan vivo.
Garis Masa Penyelidikan Hiperlipidemia MSU
2019.04
Stage 1 | Connected with the professional
This work was supported by Management & Science University (MSU) under Grant [MSU-RMC-02/FR01/08/L3/***] and the Natural Tone Sdn Bhd for providing ZACA extracts (wonderdrink6).
In this research, wonderdrink6 is called ZACA extracts. It’s an abbreviation form of Zinger officinale(Ginger), Allium sativum(Garlic), Citrus(Lemon), honey, and Malus domestica (Apple Cider)vinegar.
2019.05
Stage 3 | Research starts
ZACA extract has provided by Natural Tone Sdn Bhd for hyperlipidaemia research.
Meeting up with Professor Dr. Norshararina Shari & Santhra Segaran Balan.
2019.05
Stage 3 | Study's on going
6 groups of rats were put into research and observed by twice a day basis. Person in charge cleans the containers on daily basis, clearing off the leftover and faeces.
N.C. - Normal chow Diet (this is a reference group)
P.C. - High Cholesterol Diet
D.C. - High Cholesterol Diet, Simvastatin Drug control
W1 - High Cholesterol Diet, Consuming wonderdrink6 1mg per kg, Or equivalent to 6ml For human
W2 - High Cholesterol Diet, Consuming wonderdrink6 3mg per kg, Or equivalent to 18ml For human
W3 - High Cholesterol Diet, Consuming wonderdrink6 5mg per kg, Or equivalent to 30ml For human
2019.06
Stage 3 | Research on going
During an informal discussion between MSU and Natural Tone, we found out there is nothing changed in rats from the vivo: the only difference is group NC (normal chow diet) rats are slimmer.
2019.07
Stage 3 | Research on going
9 weeks has past. Researchers realized rat groups that administered with ZACA extracts are generally bigger than the others. Sample tested on scale shows the same too: the mentioned groups were heavier. This might be due to extra calories consumed. Both MSU and Natural Tone were worried the result will come out unexpectedly.
2019.11
Stage 4 | Sample collection
18 weeks over. Proceed to sample collection step.
At the end of the study, the rats were fasting for 12 hours. Thereafter, the rats were anesthetized with diethyl ester. The blood samples were obtained by using the cardiac puncture method. Then, the blood samples were centrifuged (3000 rpm for 15 minutes) to separate the serum. The serum (supernatant) was removed and stored at -20°C for biochemical assay. Liver, kidney, retroperitoneal adipose tissue (RpWAT), visceral fat, gonadal fat were removed, washed with saline, and weighed. The parts of the liver, kidney, RpWAT tissue were fixed in 10% NBF (neutral buffered formalin) for histological examination.
2020.09.06
First Draft has completed.
First Draft has completed.
Written by Kokila Vani Perumal.
2020.10
Result is realised
Result and discussion
Based on vitro data, ZACA extracts had ORAC value 2000 μmol TE/100 mL, TPC (7537 ± 54.5%), 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity (27.34 ± 2.71%) , Elastase inhibitory assay (29.29 ± 1.65%) and Lipoxygenase inhibitory assay (98.58 ± 1.42%). Based on vivo data, ZACA extracts treated groups reduced in bodyweight, organ weights (Liver, Adipose tissue, Kidney) and positive improvement in blood toxicity (Creatinine, AST, ALT) and lipid profile (TC, TG, LDL, HDL).
In conclusion: The results demonstrate that ZACA extracts have a hyperlipidemic activity that can be an alternative approach to combat hyperlipidemia complications
2020.11.20
Participate international scientific competition.
Management and Science University (MSU) participate in virtual 31st International Invention, Innovation & Technology Exhibition (ITEX’20), Malaysia. This Hyperlipidaemia research has won GOLD medal in Health, beauty and sports category.
2021.04.02
Participate international scientific competition.
Management and Science University (MSU) participate in virtual Malaysia Technology Expo (MTE2021), Malaysia. This Hyperlipidaemia research has won GOLD Medal in healthcare, personal care, biotechnology and life sciences category.
Pensijilan
Minuman Botani Pekat Wonderdrink 6 tidak mengandungi sebarang perisa tiruan, pewarna, sakarin, hormon, pengawet atau sebarang bahan tambahan kimia lain.
Pensijilan produk yang dikeluarkan dengan memasukkan SGS (syarikat pemeriksaan terkemuka dunia). Syarikat itu mempunyai pensijilan Halal, pensijilan Mesti, pendaftaran FoSIM di kementerian kesihatan Malaysia.
‘’Salah satu cabaran terbesar bagi Malaysia bukan sahaja ekonomi itu sendiri tetapi peningkatan perbelanjaan perubatan kerajaan untuk rakyatnya. dan di antara penyakit itu, penyakit jantung iskemik adalah yang paling teruk."
Shaiful Shah Rani
Wonderdrink6 Co Founder
Testimoni
Wonderdrink 6
Cadangan hidangan
1 botol setiap hidangan, dua kali sehari pada waktu pagi dan petang. Goncang sebati sebelum minum. Ambil 2 botol jika mengalami masalah penyumbatan saluran. Minum selepas makan jika ada masalah gastrik.
